Chronic low-level lead exposure affects the monoaminergic system in the mouse superior olivary complex
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منابع مشابه
Chronic low-level lead exposure affects the monoaminergic system in the mouse superior olivary complex.
Low-level lead (Pb) exposure is associated with behavioral and cognitive dysfunction, but it is not clear how Pb produces these behavioral changes. Pb has been shown to alter auditory temporal processing in both humans and animals. Auditory temporal processing occurs in the superior olivary complex (SOC) in the brainstem, where it is an important component in sound detection in noisy environmen...
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fibers from the cochlea. Since both cochlear nuclei impinge upon cells in the SOC, it represents the initial site of binaural interaction. The SOC is so named because anatomically it is in a superior position relative to the inferior olivary complex. The term olivary is based on the olive-shaped protuberance on the ventral lateral surface of the medulla created by the underlying inferior olivar...
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Neuronal activity is energetically costly, but despite its importance, energy production and consumption have been studied in only a few neurone types. Neuroenergetics is of special importance in auditory brainstem nuclei, where neurones exhibit various biophysical adaptations for extraordinary temporal precision and show particularly high firing rates. We have studied the development of energy...
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ژورنال
عنوان ژورنال: The Journal of Comparative Neurology
سال: 2009
ISSN: 0021-9967,1096-9861
DOI: 10.1002/cne.21978